Treatment

Like other viruses, Epstein-Barr can't be treated with antibiotics. Mono should clear up on its own without treatment in a few weeks.

What You Can Do at Home

Although no medicine can cure an EBV infection, you can take these steps at home to ease your symptoms:
  • Get plenty of rest.
  • Drink a lot of water and other liquids to stay hydrated.
  • Suck on lozenges or ice pops, or gargle with warm salt water, to make your sore throat feel better.
  • Take painkillers like acetaminophen or ibuprofen to bring down fever and relieve body aches. (Don't give aspirin to children under 19 years of age because of the risk of a rare but serious condition called Reye’s syndrome.)
Ease back into work or school, taking things slowly until you feel better. For a month or so, avoid sports, heavy lifting, or other vigorous activities in which you could injure your spleen.

Prevention

No vaccine can protect you against the EBV virus. The best way to avoid catching it is to stay away from anyone who has mono.
Don't share any items, including glasses, silverware, and toothbrushes, with someone who is infected. Also avoid kissing or having sex with an infected person.

When to See Your Doctor

There are some rare complications of mono, so see your doctor if you or your child has any of these symptoms:
  • Sudden, sharp pain on the left side of the belly, which could mean a problem with your spleen
  • Very little urine, a sign of dehydration
  • Trouble breathing or swallowing -- call 911 immediately
Also call if your symptoms don't go away after 4 to 6 weeks. You could have another type of infection besides mononucleosis.

Other Diseases Caused by EBV

EBV is best known for causing mononucleosis, but less often it can lead to other diseases, including:
Studies also show a link between EBV and multiple sclerosis (MS), but more research is needed to determine if the virus can lead to MS.